rs7743761(A;C)

4.6x increased risk of Ankylosing Spondylitis.

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
44%Average of 11 populations
On SNPedia
rs7743761(A;C)
Gene
DHFRP2

Frequency

Share of people with A;C in each HapMap population.

  • African ancestry (Southwest US)58%
  • Han Chinese (Beijing)51%
  • Mexican ancestry (Los Angeles)48%
  • Luhya (Kenya)46%
  • Gujarati Indian46%
  • Japanese (Tokyo)45%
  • Yoruba (Nigeria)41%
  • Tuscan40%
  • Maasai (Kenya)38%
  • Chinese (Denver)37%
  • European ancestry (Utah)28%

Other genotypes of rs7743761

  1. A;AMost notableBad20x increased risk of Ankylosing Spondylitis.Worth knowing · 2.012% of people
  2. C;CGoodNormal (lower) risk of Ankylosing Spondylitis.Minor · 1.945% of people

All about rs7743761

Notes

From SNPedia

Substantially increased (but still only 0.5%) risk of this rare autoimmune disease that causes inflammation of the spine and joints. Based on preliminary research. Age of onset is usually between 15 and 25, so if you are older than that, there's not much need for worry.

Source and license

Adapted from rs7743761(A;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.