rs797044948

A SNP in the VPS35 gene on chromosome 16. Its most notable genotype is C;T: Reported to be an inborn genetic disease (of unspecified type)

Gene
VPS35
Location
Chr 1646,671,766 (GRCh38)
Highest magnitude
4.4Very important
Tested on
23andMe, AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodcommon in clinvarTypical · 0.0
  2. C;TMost notableBadReported to be an inborn genetic disease (of unspecified type)Very important · 4.4

SNPedia records rs797044948 on the minus strand: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other VPS35 SNPs

All VPS35 SNPs

Notes

From SNPedia

Notes

c.1463A>G (p.Gln488Arg) Reported as a disease causing mutation in ClinVar, however, only as an unspecified "inborn genetic disease", with autosomal dominant inheritance.

C;T

see rs797044948

Source and license

Adapted from rs797044948 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.