rs799917
A SNP in the BRCA1 gene on chromosome 17. Its most notable genotype is G;G: common in clinvar
- Gene
- BRCA1
- Location
- Chr 1743,092,919 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 48%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs799917 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 26% A;G 40%
- European ancestry (Utah)G;G 43% A;G 46%
- Han Chinese (Beijing)G;G 46% A;G 42%
- Japanese (Tokyo)G;G 53% A;G 39%
- Yoruba (Nigeria)G;G 0% A;G 14%
- African ancestry (Southwest US)G;G 5% A;G 42%
- Chinese (Denver)G;G 29% A;G 54%
- Gujarati IndianG;G 25% A;G 52%
- Luhya (Kenya)G;G 2% A;G 19%
- Mexican ancestry (Los Angeles)G;G 38% A;G 41%
- Maasai (Kenya)G;G 6% A;G 39%
- TuscanG;G 35% A;G 52%
Related
Other BRCA1 SNPs
- rs28897696T;Tcarrier of two copies of BRCA1 variant; likely to be at high risk for breast/ovarian cancerVery important
- rs41286296A;CBRCA1 pathogenic mutation associated with breast cancerVery important
- rs62625306A;CBRCA1 pathogenic mutation associated with breast cancerVery important
- rs62625307A;GBRCA1 pathogenic mutation associated with breast cancerVery important
- i6051899A;Clikely to be BRCA1 variant pathogenic for breast cancerVery important
- rs1800747C;TBRCA1 pathogenic mutation associated with breast cancerVery important
- rs28897672A;Tconsidered a pathogenic BRCA1 breast cancer variantVery important
- rs28897686A;CBRCA1 pathogenic mutation associated with breast cancerVery important
Source and license
Adapted from rs799917 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.