rs80338777

A SNP in the CACNA1S gene on chromosome 1. Its most notable genotype is C;T: Malignant Hyperthermia susceptibility

Gene
CACNA1S
Location
Chr 1201,077,915 (GRCh38)
Highest magnitude
6.6Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableBadMalignant Hyperthermia susceptibilityVery important · 6.6
  2. C;CGoodcommon in clinvarTypical · 0.0

SNPedia records rs80338777 on the minus strand: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other CACNA1S SNPs

All CACNA1S SNPs

Source and license

Adapted from rs80338777 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.