rs863225332
A SNP in the APC gene on chromosome 5. Its most notable genotype is -;A: linked to certain hereditary cancers; may be a miscall in Ancestry v2c data though
- Gene
- APC
- Location
- Chr 5112,838,398 (GRCh38)
- Highest magnitude
- 4.0Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon/normal
- -;AMost notableBadlinked to certain hereditary cancers; may be a miscall in Ancestry v2c data though
On SNPedia: (-;-), (-;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other APC SNPs
- rs2229992G;TFamilial Adenomatous PolyposisVery important
- rs62619935C;TFamilial Adenomatous PolyposisVery important
- rs121913331C;TFamilial Adenomatous PolyposisVery important
- rs121913333C;TFamilial Adenomatous PolyposisVery important
- rs137854568C;TFamilial Adenomatous PolyposisVery important
- rs137854569C;GFamilial Adenomatous PolyposisVery important
- rs137854572C;TFamilial Adenomatous PolyposisVery important
- rs137854575A;CFamilial Adenomatous PolyposisVery important
Notes
From SNPedia
Notes
aka c.2804dupA (p.Tyr935Terfs)
-;A
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer
References
Source and license
Adapted from rs863225332 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.