rs864622277
A SNP in the BRIP1 gene on chromosome 17. Its most notable genotype is C;G: Ovarian cancer susceptibility
- Gene
- BRIP1
- Location
- Chr 1761,847,221 (GRCh38)
- Highest magnitude
- 6.0Very important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;GMost notableBadOvarian cancer susceptibility
- C;CGoodcommon in clinvar
SNPedia records rs864622277 on the minus strand: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other BRIP1 SNPs
- rs137852986A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs149364097C;GOvarian cancer susceptibilityVery important
- rs368796923A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs574552037C;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs575595017A;GIncreased cancer risk; ovarian cancer & relatedVery important
- rs587778134-;TTOvarian cancer susceptibilityVery important
- rs587780226A;GOvarian cancer susceptibilityVery important
- rs587780228A;CIncreased cancer risk; ovarian cancer & relatedVery important
Notes
From SNPedia
Notes
aka c.508-1G>C Considered likely pathogenic in ClinVar for hereditary cancer (breast) 23andMe name: i709076
Source and license
Adapted from rs864622277 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.