rs876657728
A SNP in the TMC1 gene on chromosome 9. Its most notable genotype is A;G: Carrier of a DFNB7/11 deafness mutation
- Gene
- TMC1
- Location
- Chr 972,805,491 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;GMost notableBadCarrier of a DFNB7/11 deafness mutation
- G;GGoodcommon in clinvar
On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other TMC1 SNPs
- rs121908072A;GDFNA36 deafness (predicted)Very important
- rs775428246C;GDFNA36 deafness (predicted)Very important
- rs786201027A;TDFNA36 deafness (predicted)Very important
- rs1387886173A;GDFNA36 deafness (predicted)Very important
- rs121908073C;TCarrier of a nonsyndromic deafness mutationImportant
- rs121908074A;GCarrier of a DFNB7/11 deafness mutationImportant
- rs121908076C;TCarrier of a DFNB7/11 deafness mutationImportant
- rs138527651C;TCarrier of a DFNB7/11 deafness mutationImportant
Notes
From SNPedia
Notes
A;G
Unaffected in absence of a second TMC1 gene mutation
Source and license
Adapted from rs876657728 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.