rs9340799(A;A)

Women have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.

Magnitude
2.0Worth knowing
Repute
Good
Frequency
62%Average of 4 populations
On SNPedia
rs9340799(A;A)
Gene
ESR1

Frequency

Share of people with A;A in each HapMap population.

  • Japanese (Tokyo)71%
  • Han Chinese (Beijing)65%
  • Yoruba (Nigeria)64%
  • European ancestry (Utah)49%

Other genotypes of rs9340799

  1. A;GGoodWomen have normal (lower) risk of Endometriosis, 0.75x lower risk of Endometrial Cancer, and normal (higher) risk of cognitive impairment.Worth knowing · 2.031% of people
  2. G;GMost notableBadWomen have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.Important · 3.07% of people

All about rs9340799

Notes

From SNPedia

Men have zero risk, but can pass this on to their daughters. This is the normal version of Estrogen Receptor 1 (alpha). It has more cognitive decline than the rare version, with old women only remembering half as much details on the East Boston Memory Test immediate recall test.

Source and license

Adapted from rs9340799(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.