rs9340799(G;G)

Women have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.

Magnitude
3.0Important
Repute
Bad
Frequency
7%Average of 4 populations
On SNPedia
rs9340799(G;G)
Gene
ESR1

Frequency

Share of people with G;G in each HapMap population.

  • Han Chinese (Beijing)10%
  • European ancestry (Utah)9%
  • Japanese (Tokyo)4%
  • Yoruba (Nigeria)3%

Other genotypes of rs9340799

  1. A;AGoodWomen have lower risk of Endometriosis but normal risk for Endometrial Cancer, and more cognitive impairment with age.Worth knowing · 2.062% of people
  2. A;GGoodWomen have normal (lower) risk of Endometriosis, 0.75x lower risk of Endometrial Cancer, and normal (higher) risk of cognitive impairment.Worth knowing · 2.031% of people

All about rs9340799

Notes

From SNPedia

Men have zero risk, but can pass it on to daughters. Endometriosis means that womb tissue grows outside the womb. This SNP is a change in Estrogen Receptor 1 (alpha). It also lowers risk of cognitive impairment in aging women - on the East Boston Memory Test immediate recall test, women with this had about 1.5 to 2.0 times greater odds of remembering story elements.

References

Source and license

Adapted from rs9340799(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.