rs9897526
A SNP in the GRN gene on chromosome 17. Its most notable genotype is G;G: common in complete genomics
- Gene
- GRN
- Location
- Chr 1744,349,572 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 19%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 56%
- European ancestry (Utah)G;G 81%
- Han Chinese (Beijing)G;G 83%
- Japanese (Tokyo)G;G 81%
- Yoruba (Nigeria)G;G 29%
- African ancestry (Southwest US)G;G 37%
- Chinese (Denver)G;G 74%
- Gujarati IndianG;G 34%
- Luhya (Kenya)G;G 22%
- Mexican ancestry (Los Angeles)G;G 72%
- Maasai (Kenya)G;G 34%
- TuscanG;G 69%
Related
Other GRN SNPs
- rs193026789A;CFrontotemporal dementia mutationVery important
- rs606231220-;CCTGFrontotemporal dementia mutationVery important
- rs606231221A;GFrontotemporal dementia mutationVery important
- rs794729669C;GFrontotemporal dementia mutationVery important
- rs794729670G;TFrontotemporal dementia mutationVery important
- rs794729671-;TFrontotemporal dementia mutationVery important
- rs794729672-;CFrontotemporal dementia mutationVery important
- rs63751243A;CLikely miscall in both 23andMe and Ancestry data; otherwise, possible frontotemporal dementia mutationImportant
Notes
From SNPedia
Notes
Associated with risk of amyotrophic lateral sclerosis (ALS) in two European populations
Source and license
Adapted from rs9897526 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.