rs1008708453
A SNP in the ABO gene on chromosome 9. Its most notable genotype is A;A: O2 alleles (ABO Type O) may be present
- Gene
- ABO
- Location
- Chr 9133,262,144 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableNot ratedO2 alleles (ABO Type O) may be present
- A;CNot ratedO2 ABO (type O) allele may be present
On SNPedia: (A;A), (A;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABO SNPs
- rs505922C;Cblood type is not O, increased risk for some diseases.Worth knowing
- rs657152A;AA few different minor risk associations; see detailsWorth knowing
- rs2519093C;Ccommon/normalTypical
- rs7853989C;CLikely blood group BTypical
- rs8176719-;-likely to be of blood type OTypical
- rs8176740A;ANo summary available.Typical
- rs8176743C;CNo summary available.Typical
- rs8176746T;TType B blood group (of ABO system)Typical
Notes
From SNPedia
Notes
ABO gene variant, known more commonly as c.53G>T or p.Arg18Leu. The rs1008708453(A) allele, as represented in dbSNP (and SNPedia) on the forward/plus strand, is reported to be completely correlated to a subtype of O type alleles known as the O2 group. These O alleles may lack the c.261delG allele that is associated with the majority of O alleles. Note that at this position, there is another variant, c.53G>A (p.Arg18Gln), which is not reported to have any particular ABO allelic association as far as we know.
A;A
see rs1008708453
A;C
see rs1008708453
Source and license
Adapted from rs1008708453 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.