rs10483774
A SNP in the ESR2 gene on chromosome 14. Its most notable genotype is G;G: common in complete genomics
- Gene
- ESR2
- Location
- Chr 1464,296,881 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 5%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageG;G 89%
- European ancestry (Utah)G;G 99%
- Han Chinese (Beijing)G;G 76%
- Japanese (Tokyo)G;G 84%
- Yoruba (Nigeria)G;G 92%
- African ancestry (Southwest US)G;G 95%
- Chinese (Denver)G;G 78%
- Luhya (Kenya)G;G 97%
- Mexican ancestry (Los Angeles)G;G 88%
- Maasai (Kenya)G;G 96%
Related
Notes
From SNPedia
Notes
Risk factors for hypospadias in the estrogen receptor 2 gene. Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling?
Source and license
Adapted from rs10483774 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.