rs1256049

rs1256049 is a SNP in the estrogen receptor 2 gene ESR2. rs1256049(A) allele carriers have higher mean carotid artery intima-media thickness (CIMT) as well as maximal CIMT, but this result may be limited to the population studied, in this case individuals from the Cardiovascular Risk in Young Finns study. [Association between single-nucleotide polymorphisms in estrogen receptor beta gene and risk of prostate cancer]. Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women. Allelic estrogen receptor 1 (ESR1) gene variants predict the outcome of ovarian stimulation in in vitro fertilization. CA repeat and RsaI polymorphisms in ERbeta gene are not associated with infertility in Indian men. Haplotypes of the estrogen receptor beta gene and breast cancer risk. Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study. Estrogen receptor beta gene haplotype is associated with pelvic organ prolapse. Association between ESR2 genetic variants and risk of myocardial infarction. Vascular actions of estrogens: functional implications. Sex steroid-related candidate genes in psychiatric disorders. Pharmacogenetics of hormone replacement therapy for climacteric symptoms. Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis. Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect. Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling? Estrogen receptor polymorphisms and the risk of endometrial cancer. A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. Association between ESR1 and ESR2 gene polymorphisms and hyperlipidemia in Chinese Han postmenopausal women. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women. Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility. Estrogen receptor gene variants are associated with anxiety disorders in older women. Oestrogen receptor polymorphisms in female patients with rheumatoid arthritis. Oestrogen receptor polymorphisms and late-life depression. Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: Evidence for association with risk and histopathological tumor characteristics in Iranian men. Are polymorphisms in oestrogen receptors genes associated with lipid levels in response to hormone therapy? Association of polymorphisms in the estrogen receptor beta (ESR2) with unexplained recurrent spontaneous abortion (URSA) in Chinese population.