rs1048709
A SNP in the CFB gene on chromosome 6. Its most notable genotype is A;A: common in clinvar
- Gene
- CFB
- Location
- Chr 631,947,158 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 17%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 3%
- European ancestry (Utah)A;A 5%
- Han Chinese (Beijing)A;A 8%
- Japanese (Tokyo)A;A 6%
- Yoruba (Nigeria)A;A 0%
- African ancestry (Southwest US)A;A 0%
- Chinese (Denver)A;A 6%
- Gujarati IndianA;A 1%
- Luhya (Kenya)A;A 0%
- Mexican ancestry (Los Angeles)A;A 2%
- Maasai (Kenya)A;A 0%
- TuscanA;A 1%
Related
Other CFB SNPs
- rs4151667A;Aage related macular degenerationImportant
- rs12614C;Ccommon in clinvarTypical
- rs522162T;Tcommon in complete genomicsTypical
- rs541862T;Tcommon on affy axiom dataTypical
- rs641153G;Gcommon in clinvarTypical
- rs1270942A;Acommon on affy axiom dataTypical
- rs3880457T;Tcommon in complete genomicsTypical
- rs4151659A;Acommon in complete genomicsTypical
Source and license
Adapted from rs1048709 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.