rs641153
A SNP in the CFB gene on chromosome 6. Its most notable genotype is G;G: common in clinvar
- Gene
- CFB
- Location
- Chr 631,946,403 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 10%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs641153 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 6 HapMap populations.
- AverageG;G 81%
- European ancestry (Utah)G;G 86%
- Yoruba (Nigeria)G;G 79%
- Chinese (Denver)G;G 92%
- Gujarati IndianG;G 62%
- Mexican ancestry (Los Angeles)G;G 83%
- TuscanG;G 84%
Related
Conditions, medicines and genes
Other CFB SNPs
- rs4151667A;Aage related macular degenerationImportant
- rs12614C;Ccommon in clinvarTypical
- rs522162T;Tcommon in complete genomicsTypical
- rs541862T;Tcommon on affy axiom dataTypical
- rs1048709A;Acommon in clinvarTypical
- rs1270942A;Acommon on affy axiom dataTypical
- rs3880457T;Tcommon in complete genomicsTypical
- rs4151659A;Acommon in complete genomicsTypical
Notes
From SNPedia
Notes
age related macular degeneration
Source and license
Adapted from rs641153 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.