rs1049296(C;C)

C1 subtype of transferrin; common in clinvar

Magnitude
0.0Typical
Repute
Good
Frequency
70%Average of 11 populations
On SNPedia
rs1049296(C;C)
Gene
TF

Frequency

Share of people with C;C in each HapMap population.

  • Yoruba (Nigeria)90%
  • Luhya (Kenya)85%
  • African ancestry (Southwest US)83%
  • European ancestry (Utah)74%
  • Mexican ancestry (Los Angeles)74%
  • Tuscan71%
  • Gujarati Indian63%
  • Maasai (Kenya)60%
  • Japanese (Tokyo)59%
  • Han Chinese (Beijing)57%
  • Chinese (Denver)57%

Other genotypes of rs1049296

  1. C;TNot ratedHeterozygote carrying both C1 and C2 transferrin subtypes; very slightly higher risk for AlzheimersMinor · 1.127% of people
  2. T;TMost notableNot ratedC2 transferrin subtype; very slightly higher risk for AlzheimersMinor · 1.23% of people

All about rs1049296

Source and license

Adapted from rs1049296(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.