rs1049296(C;T)

Heterozygote carrying both C1 and C2 transferrin subtypes; very slightly higher risk for Alzheimers

Magnitude
1.1Minor
Repute
Not rated
Frequency
27%Average of 11 populations
On SNPedia
rs1049296(C;T)
Gene
TF

Frequency

Share of people with C;T in each HapMap population.

  • Maasai (Kenya)38%
  • Chinese (Denver)38%
  • Han Chinese (Beijing)34%
  • Gujarati Indian34%
  • Japanese (Tokyo)34%
  • Tuscan28%
  • Mexican ancestry (Los Angeles)26%
  • European ancestry (Utah)24%
  • African ancestry (Southwest US)16%
  • Luhya (Kenya)16%
  • Yoruba (Nigeria)10%

Other genotypes of rs1049296

  1. C;CGoodC1 subtype of transferrin; common in clinvarTypical · 0.070% of people
  2. T;TMost notableNot ratedC2 transferrin subtype; very slightly higher risk for AlzheimersMinor · 1.23% of people

All about rs1049296

Source and license

Adapted from rs1049296(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.