rs1056837
A SNP in the CYP1B1 gene on chromosome 2. Its most notable genotype is A;A: common in clinvar
- Gene
- CYP1B1
- Location
- Chr 238,071,007 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 38%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1056837 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 25%
- European ancestry (Utah)A;A 23%
- Han Chinese (Beijing)A;A 0%
- Japanese (Tokyo)A;A 2%
- Yoruba (Nigeria)A;A 71%
- African ancestry (Southwest US)A;A 60%
- Chinese (Denver)A;A <1%
- Gujarati IndianA;A 4%
- Luhya (Kenya)A;A 54%
- Mexican ancestry (Los Angeles)A;A 5%
- Maasai (Kenya)A;A 43%
- TuscanA;A 16%
Related
Other CYP1B1 SNPs
- rs28936700C;TCarrier of a primary congenital glaucoma mutationImportant
- rs28936701A;GCarrier of a primary congenital glaucoma mutationImportant
- rs1056836C;C0.3x decreased risk for prostate cancerWorth knowing
- rs9282671T;Tsmall chance of slightly increasing risk for a form of glaucomaMinor
- rs1056827C;Ccommon in clinvarTypical
- rs1800440T;Tcommon on affy axiom dataTypical
Source and license
Adapted from rs1056837 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.