rs28936700
A SNP in the CYP1B1 gene on chromosome 2. Its most notable genotype is C;T: Carrier of a primary congenital glaucoma mutation
- Gene
- CYP1B1
- Location
- Chr 238,075,207 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- 23andMe
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;TMost notableBadCarrier of a primary congenital glaucoma mutation
- C;CGoodcommon in clinvar
SNPedia records rs28936700 on the minus strand: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other CYP1B1 SNPs
- rs28936701A;GCarrier of a primary congenital glaucoma mutationImportant
- rs1056836C;C0.3x decreased risk for prostate cancerWorth knowing
- rs9282671T;Tsmall chance of slightly increasing risk for a form of glaucomaMinor
- rs1056827C;Ccommon in clinvarTypical
- rs1056837A;Acommon in clinvarTypical
- rs1800440T;Tcommon on affy axiom dataTypical
Notes
From SNPedia
Notes
aka c.182G>A (p.Gly61Glu or G61E)
C;T
Unaffected in absence of a second CYP1B1 gene mutation
Source and license
Adapted from rs28936700 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.