rs1057910(A;C)

CYP2C9*3 carrier; average 40% reduction in warfarin metabolism

Magnitude
2.5Worth knowing
Repute
Bad
Frequency
10%Average of 9 populations
On SNPedia
rs1057910(A;C)
Gene
CYP2C9

Frequency

Share of people with A;C in each HapMap population.

  • Gujarati Indian25%
  • Tuscan15%
  • European ancestry (Utah)12%
  • Mexican ancestry (Los Angeles)11%
  • Chinese (Denver)9%
  • Han Chinese (Beijing)9%
  • African ancestry (Southwest US)5%
  • Japanese (Tokyo)4%
  • Yoruba (Nigeria)<1%

Other genotypes of rs1057910

  1. A;AGoodnormal; no effect on warfarin metabolismTypical · 0.190% of people
  2. C;CMost notableBadCYP2C9*3 homozygote; average 80% reduction in warfarin metabolism; reduced metabolism of number of other drugsVery important · 4.0<1% of people

All about rs1057910

Source and license

Adapted from rs1057910(A;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.