rs10889677(A;A)

1.5x increased risk for certain autoimmune diseases

Magnitude
1.5Minor
Repute
Bad
Frequency
21%Average of 11 populations
On SNPedia
rs10889677(A;A)
Gene
IL23R

Frequency

Share of people with A;A in each HapMap population.

  • Chinese (Denver)51%
  • Han Chinese (Beijing)51%
  • Japanese (Tokyo)49%
  • Gujarati Indian38%
  • Mexican ancestry (Los Angeles)10%
  • European ancestry (Utah)10%
  • Maasai (Kenya)9%
  • Tuscan6%
  • Luhya (Kenya)6%
  • Yoruba (Nigeria)1%
  • African ancestry (Southwest US)0%

Other genotypes of rs10889677

  1. A;CMost notableBad1.5x increased risk for certain autoimmune diseases; 2x increased risk for Graves diseaseWorth knowing · 2.038% of people
  2. C;CBadBaseline (average) risk for certain autoimmune diseases; however, 2.3x increased risk for Graves diseaseWorth knowing · 2.041% of people

All about rs10889677

Source and license

Adapted from rs10889677(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.