rs10889677(A;C)

1.5x increased risk for certain autoimmune diseases; 2x increased risk for Graves disease

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
38%Average of 11 populations
On SNPedia
rs10889677(A;C)
Gene
IL23R

Frequency

Share of people with A;C in each HapMap population.

  • Tuscan52%
  • Gujarati Indian46%
  • Chinese (Denver)44%
  • Maasai (Kenya)44%
  • Han Chinese (Beijing)41%
  • European ancestry (Utah)39%
  • Japanese (Tokyo)38%
  • Mexican ancestry (Los Angeles)35%
  • African ancestry (Southwest US)30%
  • Luhya (Kenya)29%
  • Yoruba (Nigeria)22%

Other genotypes of rs10889677

  1. A;ABad1.5x increased risk for certain autoimmune diseasesMinor · 1.521% of people
  2. C;CBadBaseline (average) risk for certain autoimmune diseases; however, 2.3x increased risk for Graves diseaseWorth knowing · 2.041% of people

All about rs10889677

Source and license

Adapted from rs10889677(A;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.