rs10889677(C;C)

Baseline (average) risk for certain autoimmune diseases; however, 2.3x increased risk for Graves disease

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
41%Average of 11 populations
On SNPedia
rs10889677(C;C)
Gene
IL23R

Frequency

Share of people with C;C in each HapMap population.

  • Yoruba (Nigeria)77%
  • African ancestry (Southwest US)70%
  • Luhya (Kenya)65%
  • Mexican ancestry (Los Angeles)55%
  • European ancestry (Utah)51%
  • Maasai (Kenya)47%
  • Tuscan43%
  • Gujarati Indian17%
  • Japanese (Tokyo)13%
  • Han Chinese (Beijing)8%
  • Chinese (Denver)5%

Other genotypes of rs10889677

  1. A;ABad1.5x increased risk for certain autoimmune diseasesMinor · 1.521% of people
  2. A;CMost notableBad1.5x increased risk for certain autoimmune diseases; 2x increased risk for Graves diseaseWorth knowing · 2.038% of people

All about rs10889677

Source and license

Adapted from rs10889677(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.