rs11200014

A SNP in the FGFR2 gene on chromosome 10. Its most notable genotype is A;A: 1.64x risk for breast cancer

Gene
FGFR2
Location
Chr 10121,575,416 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
34%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot rated1.64x risk for breast cancerTypical · 0.012% of people
  2. A;GNot rated1.20x risk for breast cancerTypical · 0.038% of people
  3. G;GNot ratedcommonTypical · 0.050% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 12% A;G 38% G;G 50%
  • European ancestry (Utah)A;A 27% A;G 40% G;G 33%
  • Han Chinese (Beijing)A;A 7% A;G 38% G;G 55%
  • Japanese (Tokyo)A;A 15% A;G 34% G;G 51%
  • Yoruba (Nigeria)A;A 8% A;G 29% G;G 64%
  • African ancestry (Southwest US)A;A 7% A;G 47% G;G 46%
  • Chinese (Denver)A;A 6% A;G 41% G;G 54%
  • Gujarati IndianA;A 12% A;G 49% G;G 40%
  • Luhya (Kenya)A;A 5% A;G 24% G;G 72%
  • Mexican ancestry (Los Angeles)A;A 17% A;G 52% G;G 31%
  • Maasai (Kenya)A;A 4% A;G 22% G;G 74%
  • TuscanA;A 26% A;G 48% G;G 27%

Conditions, medicines and genes

Other FGFR2 SNPs

All FGFR2 SNPs

Notes

From SNPedia

Notes

This SNP is basically a proxy for SNP rs1219648, which represents the SNP in the FGFR2 gene with the strongest association with breast cancer.

Source and license

Adapted from rs11200014 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.