rs1131691605
A SNP in the PROS1 gene on chromosome 3. Its most notable genotype is C;T: Partial protein-S deficiency; higher risk for blood clotting related issues
- Gene
- PROS1
- Location
- Chr 393,886,504 (GRCh38)
- Highest magnitude
- 5.0Very important
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- C;TMost notableBadPartial protein-S deficiency; higher risk for blood clotting related issues
- C;CGoodcommon/normal
- A;CBadPartial protein-S deficiency; higher risk for blood clotting related issues
SNPedia records rs1131691605 on the minus strand: (A;G), (G;G), (G;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other PROS1 SNPs
- rs387906675C;CProtein-S deficiency; severeVery important
- rs121918472G;GIncreased venous thromboembolism risk (> 6x)Very important
- rs138925964T;TClotting issues likely in infantsVery important
- rs6122A;GPartial protein-S deficiency; higher risk for blood clotting related issuesVery important
- rs121918473C;TPartial protein-S deficiency; higher risk for blood clotting related issuesVery important
- rs121918474C;TPartial protein-S deficiency; higher risk for blood clotting related issuesVery important
- rs121918475A;GPartial protein-S deficiency; higher risk for blood clotting related issuesVery important
- rs121918476C;GPartial protein-S deficiency; higher risk for blood clotting related issuesVery important
Notes
From SNPedia
Notes
two variants are represented by this SNP: c.1156-1G>A, and, c.1156-1G>T
C;T
See links via main rs-page.
A;C
See links via main rs-page.
Source and license
Adapted from rs1131691605 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.