rs11466024

A SNP in the MEFV gene on chromosome 16. Its most notable genotype is T;T: benign

Gene
MEFV
Location
Chr 163,249,468 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
2%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableNot ratedbenignMinor · 1.00% of people
  2. C;TNot ratedbenignMinor · 1.04% of people
  3. C;CGoodcommon in clinvarTypical · 0.096% of people

SNPedia records rs11466024 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageT;T 0% C;T 4% C;C 96%
  • European ancestry (Utah)T;T 0% C;T 2% C;C 99%
  • Han Chinese (Beijing)T;T 0% C;T 5% C;C 95%
  • Japanese (Tokyo)T;T 0% C;T 7% C;C 93%
  • Yoruba (Nigeria)T;T 0% C;T 2% C;C 98%

Notes

From SNPedia

Notes

T;T

While originally published as being linked to Familial Mediterranean Fever, clinvar now shows this as a benign mutation.

C;T

While originally published as being linked to Familial Mediterranean Fever, clinvar now shows this as a benign mutation.

Source and license

Adapted from rs11466024 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.