rs1208

A SNP in the NAT2 gene on chromosome 8. Its most notable genotype is A;A.

Gene
NAT2
Location
Chr 818,400,806 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
31%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedNo summary available.Typical · 0.051% of people
  2. G;GGoodcommon in clinvarTypical · 0.014% of people

On SNPedia: (A;A), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 51% G;G 14%
  • European ancestry (Utah)A;A 38% G;G 17%
  • Han Chinese (Beijing)A;A 95% G;G 0%
  • Japanese (Tokyo)A;A 95% G;G 0%
  • Yoruba (Nigeria)A;A 38% G;G 12%
  • African ancestry (Southwest US)A;A 44% G;G 16%
  • Chinese (Denver)A;A 90% G;G 2%
  • Gujarati IndianA;A 45% G;G 14%
  • Luhya (Kenya)A;A 32% G;G 26%
  • Mexican ancestry (Los Angeles)A;A 33% G;G 22%
  • Maasai (Kenya)A;A 23% G;G 24%
  • TuscanA;A 31% G;G 21%

Other NAT2 SNPs

All NAT2 SNPs

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

rs1208 is a SNP in the NAT2 gene, potentially encoding a variant detoxifying protein known as an N-acetyltransferase, but which NAT2 variant depends on which other NAT2 SNPs were also inherited. See the discussion of the NAT2 gene for a more complete explanation. The risk allele for this SNP is rs1208(G).

Source and license

Adapted from rs1208 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.