rs1799931
A SNP in the NAT2 gene on chromosome 8. Its most notable genotype is G;G: common in clinvar
- Gene
- NAT2
- Location
- Chr 818,400,860 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 7%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 86%
- European ancestry (Utah)G;G 98%
- Han Chinese (Beijing)G;G 64%
- Japanese (Tokyo)G;G 81%
- Yoruba (Nigeria)G;G 94%
- African ancestry (Southwest US)G;G 90%
- Chinese (Denver)G;G 83%
- Gujarati IndianG;G 88%
- Luhya (Kenya)G;G 96%
- Mexican ancestry (Los Angeles)G;G 66%
- Maasai (Kenya)G;G 90%
- TuscanG;G 97%
Related
Other NAT2 SNPs
- rs1799930A;ASomewhat increased risk of hearing lossWorth knowing
- rs1208A;ANo summary available.Typical
- rs1041983C;Ccommon in clinvarTypical
- rs1799929C;CNo summary available.Typical
- rs1801279G;Gcommon in complete genomicsTypical
- rs1801280T;Tcommon in clinvarTypical
- rs4986996G;Gcommon in complete genomicsTypical
- rs4986997A;Acommon in complete genomicsTypical
Genosets
- Gs140NAT2 slow metabolizerWorth knowing
- Gs139NAT2 intermediate metabolizerMinor
- Gs138NAT2 rapid metabolizerMinor
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
rs1799931 is a SNP in the NAT2 gene, potentially encoding a variant detoxifying protein known as an N-acetyltransferase, but which NAT2 variant depends on which other NAT2 SNPs were also inherited. See the discussion of the NAT2 gene for a more complete explanation. The risk allele for this SNP is rs1799931(A).
Source and license
Adapted from rs1799931 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.