rs121908831
A SNP in the TMEM127 gene on chromosome 2. Its most notable genotype is -;GCTGCTCTCAGAGA: Hereditary PGL/PCC Syndrome
- Gene
- TMEM127
- Location
- Chr 296,253,884 (GRCh38)
- Highest magnitude
- 6.2Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Goodcommon in clinvar
- -;GCTGCTCTCAGAGAMost notableBadHereditary PGL/PCC Syndrome
On SNPedia: (-;-), (-;GCTGCTCTCAGAGA). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other TMEM127 SNPs
- rs121908818C;THereditary PGL/PCC SyndromeVery important
- rs121908821C;GHereditary PGL/PCC SyndromeVery important
- rs121908825A;CHereditary PGL/PCC SyndromeVery important
- rs121908826G;THereditary PGL/PCC SyndromeVery important
- rs121908827A;GHereditary PGL/PCC SyndromeVery important
- rs121908828C;THereditary PGL/PCC SyndromeVery important
- rs121908829C;THereditary PGL/PCC SyndromeVery important
- rs121908830A;GHereditary PGL/PCC SyndromeVery important
Source and license
Adapted from rs121908831 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.