rs121964851

A SNP in the TPM3 gene on chromosome 1. Its most notable genotype is -;-: Nemaline Myopathy 1

Gene
TPM3
Location
Chr 1154,167,937 (GRCh38)
Highest magnitude
4.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. -;-Most notableBadNemaline Myopathy 1Very important · 4.0
  2. -;TAANot ratedNemaline Myopathy 1Worth knowing · 2.0
  3. AAT;AATGoodcommon in clinvarTypical · 0.0
  4. TAA;TAANot ratedNo summary available.Typical · 0.0

On SNPedia: (-;-), (-;TAA), (AAT;AAT), (TAA;TAA). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TPM3 SNPs

All TPM3 SNPs

Source and license

Adapted from rs121964851 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.