rs80358248

A SNP in the TPM3 gene on chromosome 1. Its most notable genotype is A;A: Nemaline Myopathy 1

Gene
TPM3
Location
Chr 1154,191,925 (GRCh38)
Highest magnitude
4.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GGoodcommon in clinvarTypical · 0.0
  2. A;GNot ratedNemaline Myopathy 1Worth knowing · 2.0
  3. A;AMost notableBadNemaline Myopathy 1Very important · 4.0

SNPedia records rs80358248 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other TPM3 SNPs

All TPM3 SNPs

Source and license

Adapted from rs80358248 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.