rs137852676
A SNP in the ABCC8 gene on chromosome 11. Its most notable genotype is C;C: common in clinvar
- Gene
- ABCC8
- Location
- Chr 1117,395,852 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs137852676 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABCC8 SNPs
- i5008233T;TFamilial Hyperinsulinism (ABCC8-related)Very important
- rs1048095A;GReported to be associated with permanent neonatal diabetes mellitusVery important
- rs137852672A;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344623C;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344624-;TTCCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs757110C;Ccommon in clinvarTypical
Notes
From SNPedia
Notes
[Pharmacokinetics of glaphenine in subjects with normal renal function and in patients with chronic renal insufficiency]. Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation. Genotype-phenotype associations in patients with severe hyperinsulinism of infancy. Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects. Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations. Neonatal diabetes mellitus.
Source and license
Adapted from rs137852676 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.