i5008233
A SNP in the ABCC8 gene on chromosome 11. Its most notable genotype is T;T: Familial Hyperinsulinism (ABCC8-related)
- Gene
- ABCC8
- Location
- Chr 1117,485,004 (GRCh38)
- Highest magnitude
- 4.0Very important
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AGoodnormal
- A;TBadFamilial Hyperinsulinism carrier
- T;TMost notableBadFamilial Hyperinsulinism (ABCC8-related)
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABCC8 SNPs
- rs1048095A;GReported to be associated with permanent neonatal diabetes mellitusVery important
- rs137852672A;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344623C;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344624-;TTCCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs757110C;Ccommon in clinvarTypical
- rs137852676C;Ccommon in clinvarTypical
Notes
From SNPedia
Notes
Familial Hyperinsulinism (ABCC8-related) https://www.23andme.com/you/journal/fhi/techreport/
Source and license
Adapted from i5008233 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.