rs137852672
A SNP in the ABCC8 gene on chromosome 11. Its most notable genotype is A;T: Carrier of a hyperinsulinemic hypoglycemia mutation
- Gene
- ABCC8
- Location
- Chr 1117,463,457 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- A;TMost notableBadCarrier of a hyperinsulinemic hypoglycemia mutation
- A;AGoodcommon in clinvar
SNPedia records rs137852672 on the minus strand: (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other ABCC8 SNPs
- i5008233T;TFamilial Hyperinsulinism (ABCC8-related)Very important
- rs1048095A;GReported to be associated with permanent neonatal diabetes mellitusVery important
- rs151344623C;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344624-;TTCCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs757110C;Ccommon in clinvarTypical
- rs137852676C;Ccommon in clinvarTypical
Notes
From SNPedia
Notes
aka c.560T>A (p.Val187Asp or V187D)
A;T
Unaffected in absence of a second ABCC8 gene mutation
Source and license
Adapted from rs137852672 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.