rs757110
A SNP in the ABCC8 gene on chromosome 11. Its most notable genotype is C;C: common in clinvar
- Gene
- ABCC8
- Location
- Chr 1117,396,930 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 29%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs757110 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 9%
- European ancestry (Utah)C;C 13%
- Han Chinese (Beijing)C;C 17%
- Japanese (Tokyo)C;C 14%
- Yoruba (Nigeria)C;C 0%
- African ancestry (Southwest US)C;C 4%
- Chinese (Denver)C;C 11%
- Gujarati IndianC;C 17%
- Luhya (Kenya)C;C 0%
- Mexican ancestry (Los Angeles)C;C 17%
- Maasai (Kenya)C;C 0%
- TuscanC;C 9%
Related
Other ABCC8 SNPs
- i5008233T;TFamilial Hyperinsulinism (ABCC8-related)Very important
- rs1048095A;GReported to be associated with permanent neonatal diabetes mellitusVery important
- rs137852672A;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344623C;TCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs151344624-;TTCCarrier of a hyperinsulinemic hypoglycemia mutationImportant
- rs137852676C;Ccommon in clinvarTypical
Source and license
Adapted from rs757110 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.