rs15869
A SNP in the BRCA2 gene on chromosome 13. Its most notable genotype is A;A: common in clinvar
- Gene
- BRCA2
- Location
- Chr 1332,398,875 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 74%
- European ancestry (Utah)A;A 55%
- Han Chinese (Beijing)A;A 56%
- Japanese (Tokyo)A;A 66%
- Yoruba (Nigeria)A;A 99%
- African ancestry (Southwest US)A;A 93%
- Chinese (Denver)A;A 65%
- Gujarati IndianA;A 52%
- Luhya (Kenya)A;A 97%
- Mexican ancestry (Los Angeles)A;A 79%
- Maasai (Kenya)A;A 90%
- TuscanA;A 59%
Related
Other BRCA2 SNPs
- i5009091D;Ilikely to be BRCA2 variant pathogenic for breast cancerVery important
- rs4987049A;CBRCA2 variant considered pathogenic for breast cancerVery important
- rs11571658-;TTBRCA2 variant considered pathogenic for breast cancerVery important
- rs28897743A;Gconsidered a causal BRCA2 breast cancer mutationVery important
- rs28897746C;TBRCA2 variant considered pathogenic for breast cancerVery important
- rs28897756A;ABRCA2, breast cancer mutationVery important
- rs41293477G;TBRCA2 variant considered pathogenic for breast cancerVery important
- rs41293489C;GBRCA2 variant considered pathogenic for breast cancerVery important
Source and license
Adapted from rs15869 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.