rs1800562(A;A)

Two copies of C282Y, likely affected by hemochromatosis which may be serious if male or post-menopausal.

Magnitude
5.1Very important
Repute
Bad
Frequency
0%Average of 9 populations
On SNPedia
rs1800562(A;A)
Gene
LOC108783645

Frequency

Share of people with A;A in each HapMap population.

  • European ancestry (Utah)0%
  • Han Chinese (Beijing)0%
  • Japanese (Tokyo)0%
  • Yoruba (Nigeria)0%
  • African ancestry (Southwest US)0%
  • Chinese (Denver)0%
  • Gujarati Indian0%
  • Mexican ancestry (Los Angeles)0%
  • Tuscan0%

Other genotypes of rs1800562

  1. A;GBadOne copy of C282Y, carrier of hemochromatosis, likely unaffected unless also H63D carrier.Important · 3.03% of people
  2. G;GGoodNot a C282Y hemochromatosis carrier.Typical · 0.097% of people

All about rs1800562

Notes

From SNPedia

This rare genotype causes hereditary hemochromatosis. This can result in serious iron overload in males or post-menopausal females, but is easily treated. This ACMG report recommends 4 clinical actions for those carrying two C282Y copies: * Serum ferritin concentrations should be measured to establish disease status and prognosis. * MRI to estimate parenchymal iron content, including the liver and possibly the heart * When serum ferritin and liver enzyme levels are abnormal, liver biopsy can establish or exclude cirrhosis. * Consultation with a medical geneticist and/or genetic counselor. comments at this reddit thread may be useful

Source and license

Adapted from rs1800562(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.