rs201363394
A SNP in the SERPING1 gene on chromosome 11. Its most notable genotype is T;T: Hereditary angioedema, type I
- Gene
- SERPING1
- Location
- Chr 1157,611,885 (GRCh38)
- Highest magnitude
- 4.1Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon/normal
- C;TBadCarrier of a hereditary angioedema mutation
- T;TMost notableBadHereditary angioedema, type I
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other SERPING1 SNPs
- rs28940870A;CHereditary angioedema, type IIVery important
- rs112565881G;THereditary angioedema, type IVery important
- rs121907947A;GHereditary angioedema, type IIVery important
- rs121907948A;CHereditary angioedema, type IIVery important
- rs121907949A;THereditary angioedema, type IIVery important
- rs121907950C;TPartial deficiency of complement component 4Very important
- rs121907951C;GHereditary angioedema, type IVery important
- rs281875170A;GHereditary angioedemaVery important
Notes
From SNPedia
Notes
NM_000062.2(SERPING1):c.1198C>T (p.Arg400Cys) 23andMe name: i6018370
C;T
Most likely unaffected in absence of a second SERPING1 gene mutation; see links via main rs-page and to angioedema
T;T
see links via main rs-page and to angioedema
Source and license
Adapted from rs201363394 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.