rs201381904

A SNP in the SERPINC1 gene on chromosome 1. Its most notable genotype is C;T: 10x higher venous thromboembolism risk

Gene
SERPINC1
Location
Chr 1173,909,822 (GRCh38)
Highest magnitude
7.0Very important
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CGoodcommon/normalTypical · 0.0
  2. C;TMost notableBad10x higher venous thromboembolism riskVery important · 7.0

On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Other SERPINC1 SNPs

All SERPINC1 SNPs

Notes

From SNPedia

Notes

aka c.883G>A(p.Val295Met or V295M) A 2017 study of 1,304 Chinese venous thromboembolism (VTE) patients and 1,334 healthy controls found a >10X higher risk among rs201381904(T) carriers, as oriented in dbSNP, despite having normal antithrombin levels and anticoagulant activity.

C;T

See text and links via main rs-page

Source and license

Adapted from rs201381904 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.