rs20415

A SNP in the PTGS2 gene on chromosome 1. Its most notable genotype is G;G.

Gene
PTGS2
Location
Chr 1186,681,556 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
3%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedNo summary available.Typical · 0.00% of people
  2. C;CGoodcommon in complete genomicsTypical · 0.089% of people

SNPedia records rs20415 on the minus strand: (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 8 HapMap populations.

  • AverageG;G 0% C;C 89%
  • European ancestry (Utah)G;G 0% C;C 99%
  • Han Chinese (Beijing)G;G 0% C;C 100%
  • Japanese (Tokyo)G;G 0% C;C 100%
  • Yoruba (Nigeria)G;G 0% C;C 79%
  • African ancestry (Southwest US)G;G 0% C;C 86%
  • Luhya (Kenya)G;G 0% C;C 70%
  • Mexican ancestry (Los Angeles)G;G 0% C;C 98%
  • Maasai (Kenya)G;G 0% C;C 81%

Conditions, medicines and genes

Other PTGS2 SNPs

All PTGS2 SNPs

Notes

From SNPedia

Notes

rs20415 and rs5270 prostate cancer Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

Source and license

Adapted from rs20415 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.