rs2069526

A SNP in the CYP1A2 gene on chromosome 15. Its most notable genotype is G;G: CYP1A2*1K_-739T>G homozygote

Gene
CYP1A2
Location
Chr 1574,749,000 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
6%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedCYP1A2*1K_-739T>G homozygoteTypical · 0.0<1% of people
  2. G;TNot ratedcarrier of one CYP1A2*1K_-739T>G alleleTypical · 0.013% of people
  3. T;TGoodnormalTypical · 0.086% of people

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G <1% G;T 13% T;T 86%
  • European ancestry (Utah)G;G 0% G;T <1% T;T 99%
  • Han Chinese (Beijing)G;G 0% G;T 17% T;T 83%
  • Japanese (Tokyo)G;G 0% G;T 10% T;T 90%
  • Yoruba (Nigeria)G;G 2% G;T 24% T;T 74%
  • African ancestry (Southwest US)G;G 2% G;T 23% T;T 75%
  • Chinese (Denver)G;G <1% G;T 17% T;T 82%
  • Gujarati IndianG;G 1% G;T 12% T;T 87%
  • Luhya (Kenya)G;G <1% G;T 12% T;T 87%
  • Mexican ancestry (Los Angeles)G;G 2% G;T 7% T;T 91%
  • Maasai (Kenya)G;G 0% G;T 14% T;T 86%
  • TuscanG;G 0% G;T 7% T;T 93%

Other CYP1A2 SNPs

All CYP1A2 SNPs

Genosets

Genosets combine several genotypes. Twofold checks them in your report.

Notes

From SNPedia

Notes

rs2069526 is a SNP in the CYP1A2 gene. The rs2069526(T) allele defines the CYP1A2*1K_-739T>G variant.

Source and license

Adapted from rs2069526 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.