rs2234649

A SNP in the TNFRSF1A gene on chromosome 12. Its most notable genotype is T;T: common in complete genomics

Gene
TNFRSF1A
Location
Chr 126,342,197 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
6%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TMost notableGoodcommon in complete genomicsTypical · 0.084% of people

SNPedia records rs2234649 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageT;T 84%
  • European ancestry (Utah)T;T 100%
  • Han Chinese (Beijing)T;T 80%
  • Japanese (Tokyo)T;T 86%
  • Yoruba (Nigeria)T;T 71%

Source and license

Adapted from rs2234649 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.