rs2395029(G;T)

HLA-B*5701 carrier most likely (if Caucasian or Hispanic)

Magnitude
3.2Important
Repute
Bad
Frequency
8%Average of 11 populations
On SNPedia
rs2395029(G;T)
Gene
HCP5

Frequency

Share of people with G;T in each HapMap population.

  • Gujarati Indian31%
  • Maasai (Kenya)26%
  • European ancestry (Utah)12%
  • Luhya (Kenya)6%
  • Tuscan6%
  • Mexican ancestry (Los Angeles)5%
  • Han Chinese (Beijing)3%
  • Chinese (Denver)2%
  • African ancestry (Southwest US)2%
  • Japanese (Tokyo)0%
  • Yoruba (Nigeria)0%

Other genotypes of rs2395029

  1. G;GMost notableBadHLA-B*5701 homozygote likely if Caucasian or Hispanic; high risk for hypersensitivity to various drugs including abacavir; 2x psoriasis risk; see detailsVery important · 4.0<1% of people
  2. T;TGoodcommonTypical · 0.091% of people

All about rs2395029

Notes

From SNPedia

risk for hypersensitivity to various drugs including abacavir This genotype is associated with an HIV viral load 1 log (10 fold) lower than the most common genotype (rs2395029(T;T)). PMID 17641165 Possible 2x higher risk for psoriasis See also rs2395029 and HIV. The (G) allele frequency is only 0.05 which means only about 1 in 10 people have this genotype.

References

Source and license

Adapted from rs2395029(G;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.