rs2488457(G;G)

Common/normal

Magnitude
0.0Typical
Repute
Good
Frequency
14%Average of 11 populations
On SNPedia
rs2488457(C;C)Minus strand
Gene
PTPN22

Frequency

Share of people with G;G in each HapMap population.

  • Chinese (Denver)44%
  • Han Chinese (Beijing)42%
  • Japanese (Tokyo)30%
  • Mexican ancestry (Los Angeles)14%
  • European ancestry (Utah)7%
  • Gujarati Indian6%
  • Tuscan5%
  • African ancestry (Southwest US)2%
  • Yoruba (Nigeria)0%
  • Luhya (Kenya)0%
  • Maasai (Kenya)0%

Other genotypes of rs2488457

  1. C;GBadSlightly increased (~1.5x) risk for certain autoimmune diseases in some populationsMinor · 1.528% of people
  2. C;CMost notableBadSlightly increased (~1.7x) risk for certain autoimmune diseases in some populationsMinor · 1.759% of people

All about rs2488457

Source and license

Adapted from rs2488457(C;C) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.