rs2511988
A SNP in the SERPING1 gene on chromosome 11. Its most notable genotype is A;A: common in clinvar
- Gene
- SERPING1
- Location
- Chr 1157,611,697 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 49%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2511988 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 31%
- European ancestry (Utah)A;A 16%
- Han Chinese (Beijing)A;A 59%
- Japanese (Tokyo)A;A 58%
- Yoruba (Nigeria)A;A 26%
- African ancestry (Southwest US)A;A 23%
- Chinese (Denver)A;A 55%
- Gujarati IndianA;A 12%
- Luhya (Kenya)A;A 26%
- Mexican ancestry (Los Angeles)A;A 33%
- Maasai (Kenya)A;A 22%
- TuscanA;A 10%
Related
Other SERPING1 SNPs
- rs28940870A;CHereditary angioedema, type IIVery important
- rs112565881G;THereditary angioedema, type IVery important
- rs121907947A;GHereditary angioedema, type IIVery important
- rs121907948A;CHereditary angioedema, type IIVery important
- rs121907949A;THereditary angioedema, type IIVery important
- rs121907950C;TPartial deficiency of complement component 4Very important
- rs121907951C;GHereditary angioedema, type IVery important
- rs201363394T;THereditary angioedema, type IVery important
Source and license
Adapted from rs2511988 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.