rs3024866
A SNP in the STAT4 gene on chromosome 2. Its most notable genotype is G;G: common in clinvar
- Gene
- STAT4
- Location
- Chr 2191,058,115 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 46%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs3024866 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 35%
- European ancestry (Utah)G;G 10%
- Han Chinese (Beijing)G;G 26%
- Japanese (Tokyo)G;G 21%
- Yoruba (Nigeria)G;G 81%
- African ancestry (Southwest US)G;G 66%
- Chinese (Denver)G;G 22%
- Gujarati IndianG;G 15%
- Luhya (Kenya)G;G 77%
- Mexican ancestry (Los Angeles)G;G 19%
- Maasai (Kenya)G;G 45%
- TuscanG;G 6%
Related
Other STAT4 SNPs
- rs7574865T;T1.69x risk of rheumatoid arthritis; 2.4x risk of SLE; 2.28x risk of Sjögren's syndrome; increased risk of type-1 diabetes; and increased risk of primary biliary cirrhosis.Important
- rs3821236A;A2x higher risk of lupusWorth knowing
- rs10181656G;G1.7x increased SLE riskWorth knowing
- rs7582694C;C1.71x increased SLE riskTypical
- rs10168266C;Cnormal risk of Sjogren's syndromeTypical
Source and license
Adapted from rs3024866 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.