rs3135753
A SNP in the FGFR2 gene on chromosome 10. Its most notable genotype is T;T: common genotype
- Gene
- FGFR2
- Location
- Chr 10121,521,144 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs3135753 on the minus strand: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageT;T 100%
- European ancestry (Utah)T;T 99%
- Han Chinese (Beijing)T;T 100%
- Japanese (Tokyo)T;T 100%
- Yoruba (Nigeria)T;T 100%
Related
Other FGFR2 SNPs
- rs2981582A;A1.7x higher risk of ER+ breast cancerImportant
- rs3750817T;T0.64x reduced risk for breast cancer, and higher likelihood of favorable postmenopausal hormone therapyWorth knowing
- rs1219648G;G1.64x risk for breast cancerWorth knowing
- rs2420946T;T1.64x risk for breast cancerWorth knowing
- rs4752566G;Tassociated with thicker hair in AsiansMinor
- rs755793A;Acommon in complete genomicsTypical
- rs1047100T;Tcommon in clinvarTypical
- rs2303568A;Acommon in complete genomicsTypical
Source and license
Adapted from rs3135753 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.