rs363039

A SNP in the SNAP25 gene on chromosome 20. Its most notable genotype is C;T.

Gene
SNAP25
Location
Chr 2010,239,848 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
45%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. C;TMost notableNot ratedNo summary available.Typical · 0.00% of people
  2. G;GNot ratedNo summary available.Typical · 0.028% of people
  3. A;ANot ratedNo summary available.Typical · 0.021% of people

SNPedia records rs363039 on the minus strand: (A;G), (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;T 0% G;G 28% A;A 21%
  • European ancestry (Utah)C;T 0% G;G 38% A;A 15%
  • Han Chinese (Beijing)C;T 0% G;G 17% A;A 38%
  • Japanese (Tokyo)C;T 0% G;G 16% A;A 29%
  • Yoruba (Nigeria)C;T 0% G;G 31% A;A 19%
  • African ancestry (Southwest US)C;T 0% G;G 30% A;A 18%
  • Chinese (Denver)C;T 0% G;G 23% A;A 26%
  • Gujarati IndianC;T 0% G;G 43% A;A 11%
  • Luhya (Kenya)C;T 0% G;G 30% A;A 18%
  • Mexican ancestry (Los Angeles)C;T 0% G;G 21% A;A 19%
  • Maasai (Kenya)C;T 0% G;G 22% A;A 21%
  • TuscanC;T 0% G;G 34% A;A 18%

Other SNAP25 SNPs

All SNAP25 SNPs

Notes

From SNPedia

Notes

This is one of four SNPs in the first intron of the SNAP25 gene that have been correlated with increased intelligence based on studies of ~300 Caucasian subjects. In orientation to the dbSNP entry for this SNP, rather than as published, the (C;C) genotype averages ~2 PIQ points higher than the (C;T) genotype, which averages 2 PIQ points higher than the (T;T) genotype. For SNPs rs363039 - rs363043 - rs353016, respectively, the haplotype C-T-T is most associated with higher intelligence in children, whereas the haplotype C-C-T is most associated in adults (SNPs oriented as in dbSNP).

Source and license

Adapted from rs363039 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.