rs3758505
A SNP in the IDE gene on chromosome 10. Its most notable genotype is A;A: common in complete genomics
- Gene
- IDE
- Location
- Chr 1092,575,021 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 18%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs3758505 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 63%
- European ancestry (Utah)A;A 86%
- Han Chinese (Beijing)A;A 77%
- Japanese (Tokyo)A;A 57%
- Yoruba (Nigeria)A;A 36%
- African ancestry (Southwest US)A;A 35%
- Chinese (Denver)A;A 79%
- Gujarati IndianA;A 70%
- Luhya (Kenya)A;A 39%
- Mexican ancestry (Los Angeles)A;A 71%
- Maasai (Kenya)A;A 58%
- TuscanA;A 87%
Related
Conditions, medicines and genes
Other IDE SNPs
- rs6583817C;T~0.80x (lower) risk for late onset Alzheimer's diseaseMinor
- rs7910977C;T~0.80x (lower) risk for late onset Alzheimer's diseaseMinor
- rs3781239C;Ccommon in complete genomicsTypical
- rs4646954G;Gcommon in complete genomicsTypical
- rs4646958T;Tcommon in complete genomicsTypical
- rs7895832A;Acommon in complete genomicsTypical
- rs17107734C;Ccommon in complete genomicsTypical
Notes
From SNPedia
Notes
rs3758505, rs4646953 and rs4646954 influence Alzheimer's disease
Source and license
Adapted from rs3758505 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.