rs3761847(A;G)

1.32 x risk of rheumatoid arthritis.

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
50%Average of 11 populations
On SNPedia
rs3761847(A;G)
Gene
TRAF1

Frequency

Share of people with A;G in each HapMap population.

  • Chinese (Denver)60%
  • Yoruba (Nigeria)57%
  • Mexican ancestry (Los Angeles)55%
  • European ancestry (Utah)55%
  • African ancestry (Southwest US)54%
  • Han Chinese (Beijing)50%
  • Japanese (Tokyo)50%
  • Tuscan44%
  • Maasai (Kenya)42%
  • Gujarati Indian42%
  • Luhya (Kenya)41%

Other genotypes of rs3761847

  1. A;AGoodnormalTypical · 0.025% of people
  2. G;GMost notableBad>1.32 x risk of rheumatoid arthritisWorth knowing · 2.225% of people

All about rs3761847

Notes

From SNPedia

A common genetic variant at the TRAF1-C5 locus on chromosome 9 is associated with an increased risk of anti-CCP-positive rheumatoid arthritis. rs3761847, a SNP located between two genes associated with chronic inflammation (TRAF1 and C5), is associated with increased risk of anti CCP-positive rheumatoid arthritis. The risk allele is (G); the odds ratio reported is 1.32 (95% confidence interval, 1.23 to 1.42; P=4x10-14) PMID 17804836.

References

Source and license

Adapted from rs3761847(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.